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1

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

Bruce, Annadora J., Boling, Warren, Kindy, Mark S., Peschon, Jacques, Kraemer, Philipp J., Carpenter, Melissa K., Holtsberg, Frederick W., Mattson, Mark P.

Journal:

Nature Medicine

Year:

1996

File:

PDF, 1.07 MB

1996

2

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins

Quiroz, Jose A., Malonis, Ryan J., Thackray, Larissa B., Cohen, Courtney A., Pallesen, Jesper, Jangra, Rohit K., Brown, Rebecca S., Hofmann, Daniel, Holtsberg, Frederick W., Shulenin, Sergey, Nyakatur

Journal:

Year:

2019

Language:

english

File:

PDF, 4.27 MB

english, 2019

3

Lysophosphatidic acid and apoptosis of nerve growth factor-differentiated PC12 cells

Frederick W. Holtsberg, Marion R. Steiner, Annadora J. Bruce-Keller, Jeffrey N. Keller, Mark P. Mattson, John C. Moyers, Sheldon M. Steiner

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 136 KB

english, 1998

4

Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations

Qing Guo, Weiming Fu, Frederick W. Holtsberg, Sheldon M. Steiner, Mark P. Mattson

Journal:

Journal of Neuroscience Research

Year:

1999

Language:

english

File:

PDF, 658 KB

english, 1999

5

Incidence and distribution of argininosuccinate synthetase deficiency in human cancers : A method for identifying cancers sensitive to arginine deprivation

Brian J. Dillon, Victor G. Prieto, Steven A. Curley, C. Mark Ensor, Frederick W. Holtsberg, John S. Bomalaski, Mike A. Clark

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

6

Lysophosphatidic Acid Induces a Sustained Elevation of Neuronal Intracellular Calcium

Frederick W. Holtsberg, Marion R. Steiner, Katsutoshi Furukawa, Jeffrey N. Keller, Mark P. Mattson, Sheldon M. Steiner

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 705 KB

english, 1997

7

Lysophosphatidic Acid-Induced Proliferation-Related Signals in Astrocytes

Jeffrey N. Keller, Marion R. Steiner, Frederick W. Holtsberg, Mark P. Mattson, Sheldon M. Steiner

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.04 MB

english, 1997

8

Lysophosphatidic Acid Induces Necrosis and Apoptosis in Hippocampal Neurons

Frederick W. Holtsberg, Marion R. Steiner, Jeffrey N. Keller, Robert J. Mark, Mark P. Mattson, Sheldon M. Steiner

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.27 MB

english, 1998

9

Lysophosphatidic Acid Induction of Neuronal Apoptosis and Necrosis

MARION R. STEINER, FREDERICK W. HOLTSBERG, JEFFREY N. KELLER, MARK P. MATTSON, SHELDON M. STEINER

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 834 KB

english, 2000

10

Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD

Annadora J Bruce-Keller, James W Geddes, Pamela E Knapp, Robert W McFall, Jeffrey N Keller, Frederick W Holtsberg, Sampath Parthasarathy, Sheldon M Steiner, Mark P Mattson

Journal:

Journal of Neuroimmunology

Year:

1999

Language:

english

File:

PDF, 3.01 MB

english, 1999

11

Poly(ethylene glycol) (PEG) conjugated arginine deiminase: effects of PEG formulations on its pharmacological properties

Frederick W. Holtsberg, Charles Mark Ensor, Marion R. Steiner, John S. Bomalaski, Mike A. Clark

Journal:

Journal of Controlled Release

Year:

2002

Language:

english

File:

PDF, 458 KB

english, 2002

12

Repeated Chair Stands as a Measure of Lower Limb Strength in Sexagenarian Women

McCarthy, E. K., Horvat, M. A., Holtsberg, P. A., Wisenbaker, J. M.

Journal:

The Journals of Gerontology Series A Biological Sciences and Medical Sciences

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

13

A nearly unbiased inherently stable bearings-only tracker

Holtsberg, A., Holst, J.H.

Journal:

IEEE Journal of Oceanic Engineering

Year:

1993

Language:

english

File:

PDF, 381 KB

english, 1993

14

[IEEE Comput. Soc. Press [1991] Conference Record of the Twenty-Fifth Asilomar Conference on Signals, Systems & Computers - Pacific Grove, CA, USA (4-6 Nov. 1991)] [1991] Conference Record of the Twenty-Fifth Asilomar Conference on Signals, Systems & Computers - On target manoeuvres in bearings only tracking (sonar)

Holst, J., Holtsberg, A.

Year:

1991

Language:

english

File:

PDF, 381 KB

english, 1991

15

A tripartite cocktail of chimeric monoclonal antibodies passively protects mice against ricin, staphylococcal enterotoxin B and Clostridium perfringens epsilon toxin

Sully, Erin K., Whaley, Kevin, Bohorova, Natasha, Bohorov, Ognian, Goodman, Charles, Kim, Do, Pauly, Michael, Velasco, Jesus, Holtsberg, Frederick W., Stavale, Eric, Aman, M. Javad, Tangudu, Chandra,

Journal:

Year:

2014

Language:

english

File:

PDF, 820 KB

english, 2014

16

[IEEE Comput. Soc. Press [1991] Conference Record of the Twenty-Fifth Asilomar Conference on Signals, Systems & Computers - Pacific Grove, CA, USA (4-6 Nov. 1991)] [1991] Conference Record of the Twenty-Fifth Asilomar Conference on Signals, Systems & Computers - Estimation and confidence in bearings only tracking

Holtsberg, A., Holst, J.

Year:

1991

Language:

english

File:

PDF, 358 KB

english, 1991

17

Quantitative Serology Assays for Determination of Antibody Responses to Ebola Virus Glycoprotein and Matrix Protein in Nonhuman Primates and Humans

Vu, Hong, Shulenin, Sergey, Grolla, Allen, Audet, Jonathan, He, Shihua, Kobinger, Gary, Unfer, Robert C., Warfield, Kelly L., Aman, M. Javad, Holtsberg, Frederick W.

Journal:

Antiviral Research

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

18

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Howell, Katie A., Patel, Sonal J., Gunn, Bronwyn, Karim, Marcus, Lai, Jonathan R., Frei, Julia C., Nyakatura, Elisabeth K., Zeitlin, Larry, Douglas

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 3.13 MB

english, 2016

19

Development of a novel multiplex electrochemiluminescent-based immunoassay for quantification of human serum IgG against 10 Staphylococcus aureus toxins

Adhikari, Rajan P., Haudenschild, Christian, Sterba, Patricia M., Sahandi, Sara, Enterlein, Sven, Holtsberg, Frederick W., Aman, M. Javad

Journal:

Journal of Immunological Methods

Year:

2016

Language:

english

File:

PDF, 2.27 MB

english, 2016

20

Mini-Mental State Exam Status of Community-Dwelling Cognitively Intact Centenarians

Holtsberg, Philip A., Poon, Leonard W., Noble, Carol A., Martin, Peter

Journal:

International Psychogeriatrics

Year:

1995

Language:

english

File:

PDF, 729 KB

english, 1995

21

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

Howell, Katie A., Qiu, Xiangguo, Brannan, Jennifer M., Bryan, Christopher, Davidson, Edgar, Holtsberg, Frederick W., Wec, Anna Z., Shulenin, Sergey, Biggins, Julia E., Douglas, Robin, Enterlein, Sven

Journal:

Year:

2016

Language:

english

File:

PDF, 3.35 MB

english, 2016

22

A "Trojan horse" bispecific antibody strategy for broad protection against ebolaviruses

Wec, A. Z., Nyakatura, E. K., Herbert, A. S., Howell, K. A., Holtsberg, F. W., Bakken, R. R., Mittler, E., Christin, J. R., Shulenin, S., Jangra, R. K., Bharrhan, S., Kuehne, A. I., Bornholdt, Z. A.,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

23

Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor α and endotoxin

THOMAS, J. Brandon, HOLTSBERG, Frederick W., ENSOR, C. Mark, BOMALASKI, John S., CLARK, Mike A.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

24

Butyric acid-induced differentiation of HL-60 cells increases the expression of a single lysophospholipase

Garsetti, D, Holtsberg, F, Steiner, M R, Egan, R W, Clark, M A

Journal:

Biochemical Journal

Year:

1992

Language:

english

File:

PDF, 1.66 MB

english, 1992

25

Presence in human eosinophils of a lysophospholipase similar to that found in the pancreas

Holtsberg, F W, Ozgur, L E, Garsetti, D E, Myers, J, Egan, R W, Clark, M A

Journal:

Biochemical Journal

Year:

1995

Language:

english

File:

PDF, 916 KB

english, 1995

26

Enzymic degradation of plasma arginine using arginine deiminase inhibits nitric oxide production and protects mice from the lethal effects of tumour necrosis factor α and endotoxin

THOMAS, J. Brandon, HOLTSBERG, Frederick W., ENSOR, C. Mark, BOMALASKI, John S., CLARK, Mike A.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

27

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute HCV infection

Keck, Zhen-Yong, Wang, Yong, Lau, Patrick, Lund, Garry, Rangarajan, Sneha, Fauvelle, Catherine, Liao, Grant C., Holtsberg, Frederick W., Warfield, Kelly L., Aman, M. Javad, Pierce, Brian G., Fuerst, T

Journal:

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

28

The safety and immunogenicity of a parenterally administered structure-based rationally modified recombinant Staphylococcal enterotoxin B protein vaccine, STEBVax

Chen, Wilbur H., Pasetti, Marcela F., Adhikari, Rajan P., Baughman, Holly, Douglas, Robin, El-Khorazaty, Jill, Greenberg, Nancy, Holtsberg, Frederick W., Liao, Grant C., Reymann, Mardi K., Wang, Xiaol

Journal:

Clinical and Vaccine Immunology

Year:

2016

Language:

english

File:

PDF, 701 KB

english, 2016

29

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.

Keller, J N, Kindy, M S, Holtsberg, F W, {St Clair}, D K, Yen, H C, Germeyer, a, Steiner, S M, Bruce-Keller, a J, Hutchins, J B, Mattson, M P

Journal:

The Journal of neuroscience : the official journal of the Society for Neuroscience

Year:

1998

Language:

english

File:

PDF, 711 KB

english, 1998

30

Uricase formulated with polyethylene glycol (Uricase-PEG 20): Biochemical rationale and preclinical studies

Bomalaski, John S., Holtsberg, Frederick W., Ensor, C. Mark, Clark, Mike a.

Journal:

The Journal of Rheumatology

Year:

2002

Language:

english

File:

PDF, 537 KB

english, 2002

31

Interactive Target Tracking in the Bearing-Time Plot

Karlsson, N., Holtsberg, A., Holst, J.

Journal:

IFAC Proceedings Volumes

Year:

1996

Language:

english

File:

PDF, 343 KB

english, 1996

32

A Modelling Technique for Estimating Hot Tap Water Consumption in District Heating Systems

Jónsson, G R, Holtsberg, A, Jónsson, V K

Journal:

Proceedings of the Institution of Mechanical Engineers Part A Journal of Power and Energy

Year:

1994

Language:

english

File:

PDF, 777 KB

english, 1994

33

Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Keller, Jeffrey N., Kindy, Mark S., Holtsberg, Fredrick W., St. Clair, Daret K., Yen, Hsiu-Chuan, Germeyer, Arriane, Steiner, Sheldon M., Bruce-Keller, Annadora J., Hutchins, James B., Mattson, Mark P

Journal:

Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 711 KB

english, 1998

34

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs

Fusco, Marnie L., Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E., Murin, Charles D., Warfield, Kelly L., Li, Sheng, Holtsberg, Frederick W., Shulenin, Sergey, Vu, Hong, Olinger, Gene G., Kim, Do

Journal:

Year:

2015

Language:

english

File:

PDF, 2.01 MB

english, 2015

35

Efficacy of Ebola Glycoprotein-Specific Equine Polyclonal Antibody Product Against Lethal Ebola Virus Infection in Guinea Pigs

Chan, Mable, Holtsberg, Frederick W, Vu, Hong, Howell, Katie A, Leung, Anders, Van der Hart, Evelyn, Walz, Paul H, Aman, M Javad, Kodihalli, Shantha, Kobasa, Darwyn

Journal:

The Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 319 KB

english, 2018

36

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms

Warfield, Kelly L, Howell, Katie A, Vu, Hong, Geisbert, Joan, Wong, Gary, Shulenin, Sergey, Sproule, Stephanie, Holtsberg, Frederick W, Leung, Daisy W, Amarasinghe, Gaya K, Swenson, Dana L, Bavari, Si

Journal:

The Journal of Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 319 KB

english, 2018

37

Effective Treatment of Staphylococcal Enterotoxin B (SEB) Aerosol Intoxication in Rhesus Macaques using two parentally-administered High Affinity Monoclonal Antibodies

Verreault, Daniel, Ennis, Jane, Whaley, Kevin, Killeen, Stephanie Z., Karauzum, Hatice, Aman, M. M. Javad, Holtsberg, Rick, Doyle-Meyers, Lara, Didier, Peter J., Zeitlin, Larry, Roy, Chad J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2019

Language:

english

File:

PDF, 1.40 MB

english, 2019

38

Potent Neutralization of Staphylococcal Enterotoxin B in vivo by Antibodies that Block Binding to the T-Cell Receptor

Chen, Gang, Karauzum, Hatice, Long, Hua, Carranza, Danielle, Holtsberg, Frederick W., Howell, Katie A., Abaandou, Laura, Zhang, Bojie, Jarvik, Nick, Ye, Wei, Liao, Grant C., Gross, Michael L., Leung,

Journal:

Journal of Molecular Biology

Year:

2019

Language:

english

File:

PDF, 5.55 MB

english, 2019

39

Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)

Kailasan, Shweta, Kort, Thomas, Mukherjee, Ipsita, Liao, Grant C., Kanipakala, Tulasikumari, Williston, Nils, Ganjbaksh, Nader, Venkatasubramaniam, Arundhathi, Holtsberg, Frederick W., Karauzum, Hatic

Journal:

Year:

2019

Language:

english

File:

PDF, 3.52 MB

english, 2019

40

Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)

Kailasan, Shweta, Kort, Thomas, Mukherjee, Ipsita, Liao, Grant C., Kanipakala, Tulasikumari, Williston, Nils, Ganjbaksh, Nader, Venkatasubramaniam, Arundhathi, Holtsberg, Frederick W., Karauzum, Hatic

Journal:

Year:

2019

File:

PDF, 3.52 MB

2019

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